Which genetic factor is associated with high cholesterol?

The association between hereditary conditions and high cholesterol is well-documented. Certain genetic factors can lead to dyslipidemia, which is characterized by abnormal levels of lipids in the blood, including elevated cholesterol levels. For example, familial hypercholesterolemia is a hereditary condition that significantly increases the risk of high cholesterol due to a genetic mutation affecting LDL cholesterol receptors. Individuals with this condition may require early interventions to manage their cholesterol levels effectively.

In contrast, while variations in exercise habits and caloric restriction can influence cholesterol levels, these are more behavioral and lifestyle factors rather than genetic ones. Vitamin deficiencies may impact overall health but are not directly linked as a primary cause of high cholesterol levels. Therefore, hereditary conditions stand out as a key genetic factor influencing cholesterol levels.